… to a successful drug development program and US Food and Drug Administration (FDA) …
provides a comprehensive summary of the clinical pharmacokinetic and pharmacodynamic …

… in pharmaceutical drug discovery to address unwanted pharmacological side effects of
drug … allows to exploit synergies for comprehensive safety assessment of drug candidates. …

… pharmacokinetic/pharmacodynamic studies in dosing optimization and decision making in
antimicrobial drug development. … a comprehensive review of the development process of all …

… drug discovery. Many physicochemical properties of drugs like toxicity, absorption, drug‐drug …
tremendous potential in the field of drug discovery. Techniques discussed in this review …

… and inform novel drug development for treating … integration effect for the identification of
more lead compounds that could be the foundation for the discovery of new anti-tumor drugs. …

… Drug dosing in neonates should be based on integrated knowledge concerning the disease
… neonate, and the pharmacokinetics (PK) and pharmacodynamics (PD) of a given drug. It is …

… in pharmacokinetics (PK), pharmacodynamics (PD) and pharmacogenetics (PGx), and
occurrence of drug … To date, comprehensive reviews in ADRs of AChEIs have so far been scarcely …

Apararenone is a long‐acting, nonsteroidal mineralocorticoid receptor antagonist (MRA). The
safety, tolerability, and pharmacokinetic (PK) and pharmacodynamic (PD) profiles of single…

… drug to market;16 (4) Stringent regulatory requirements: The process of drug development is
heavily regulated, and drugs … drug development: Even after a drug has been identified and …

… discovery field. Herein, we present the different … in the drug discovery domain. We believe
that this report would serve as a comprehensive guide towards computational-oriented drug …