… as a new class of antivirus drugs that efficiently interact with the ion channel of the influenza
A virus M2 protein. The binding and blockage of the M2 ion channel were modeled, and the …

… ion channels known as A/M2 and BM2, respectively. The A/M2 channel is the target of the
antiviral … of proton conductance of the viral ion channels are described and the review makes a …

… 7 indicated that the target of antiviral action is the hydropho… ion channel activity. The
concentrations of the drug used to … in testing the associated ion channel activity of MP proteins …

… target for action of the antiviral drug amantadine. Thus, these proteins are also important
because they are important therapeutic targets … antiviral drugs that inhibit the M2 ion channel …

… led to the development of curative antiviral therapy. Moreover, … inhibitors for antagonizing p7
ion channel/pore-like activity. … disruption of ionic gradients across target membranes thereby …

… E5 encodes ion channel activity highlights a potential therapeutic opportunity [5]. Virus-encoded
ion channels (viroporins) of other viruses have been shown to be viable drug targets. In …

… Many compounds are in the pipeline yet primarily target only three viral proteins… ion channel,
or “viroporin,” whose essential functions represent a clinically proven class of antiviral target …

… target of antiviral drugs is to block the viral replication cycle at any of these stages. Currently,
there are more than eighty antiviral … is crucial in forming ion channels in host cell membranes…

… antiviral drugs approved to treat influenza virus infections are currently limited to two targets,
the viral neuraminidase and the viral ion channel… antiviral strategies targeting these viruses. …

… This paper reviews the progress of small molecular inhibitors act as antiviral … M2 ion channel
protein inhibitors etc. Moreover, we also summarize new, recently reported potential targets …