… of imatinib vs imatinib/interferon-alpha vs imatinib/low-dose AraC vs imatinib after interferon-alpha failure in newly diagnosed chronic phase chronic myeloid leukemia

…, R Hehlmann, German CML Study Group - Annals of …, 2004 - Springer
… reverse transcriptase polymerase chain reaction (RT-PCR) … approach is feasible regarding
efficacy and safety. However, … -treatment in the elderly with chronic myelogenous leukemia (…

Hematological and molecular response Evaluation of patients with chronic myeloid Leukemia on treatment with imatinib

B John - 2010 - search.proquest.com
polymerase chain reaction (RT-PCR) virtually all patients .… in which therapy with a biologic
agent, interferon alpha (INF-α… a standard tool for monitoring CML patients. Also, cytogenetics …

Molecular monitoring of BCR-ABL transcripts in patients with chronic myelogenous leukemia: is high sensitivity of clinical value?

M Norkin, CA Schiffer - Current hematologic malignancy reports, 2010 - Springer
… (CML) in chronic phase (CP). … in determining the effectiveness of initial therapy, estimating
compliance with … ’ quantitative reverse transcriptase polymerase chain reaction of fusion gene …

Monitoring minimal residual disease and controlling drug resistance in chronic myeloid leukaemia patients in treatment with imatinib as a guide to clinical …

G Martinelli, I Iacobucci, S Soverini… - Hematological …, 2006 - Wiley Online Library
… , were established for patients on interferon alpha. They have … reverse transcriptase
polymerase chain reaction of fusion … in patients with chronic myelogenous leukemia in chronic

[HTML][HTML] The role of cytogenetics and molecular biology in the diagnosis, treatment and monitoring of patients with chronic myeloid leukemia

LE Dorfman, MA Floriani, TMRDR Oliveira… - Jornal Brasileiro de …, 2018 - SciELO Brasil
… techniques such as FISH or polymerase chain reaction (PCR) ( 19 19 … in chronic myelogenous
leukemia cells through nuclear … The use of interferon-alpha resulted in disease regression …

Fluorescent in situ hybridization in the diagnosis, prognosis, and treatment monitoring of chronic myeloid leukemia

AP Landstrom, A Tefferi - Leukemia & lymphoma, 2006 - Taylor & Francis
… (FISH) and reverse-transcriptase polymerase chain reaction (RT-PCR) feature higher … 38
months) and the prognostic performance of the FISH-apparent genetic heterogeneity was found …

… transcripts by quantitative reverse transcriptase–polymerase chain reaction predicts outcome after allogeneic stem cell transplantation for chronic myeloid leukemia

E Olavarria, E Kanfer, R Szydlo, J Kaeda… - Blood, The Journal …, 2001 - ashpublications.org
… (RT-PCR) has become widely used for monitoring minimal … , and death without relapse was
the competing risk. The log-rank … or were treated with hydroxyurea, interferon-alpha, and/or …

Standardized definitions of molecular response in chronic myeloid leukemia

NCP Cross, HE White, MC Müller, G Saglio… - Leukemia, 2012 - nature.com
Monitoring CML patients responding to treatment with … after interferon-alpha therapy
for chronic myelogenous leukemia: … reverse-transcriptase polymerase chain reaction (RQ-PCR)—…

[HTML][HTML] Establishing optimal quantitative-polymerase chain reaction assays for routine diagnosis and tracking of minimal residual disease in JAK2-V617F-associated …

JV Jovanovic, A Ivey, AM Vannucchi, E Lippert… - Leukemia, 2013 - nature.com
… On the basis of experience of molecular monitoring in other … slope associated with a PCR
reaction with maximal efficiency). y-… vera patients treated with pegylated interferon alpha-2a. …

[HTML][HTML] Molecular measurement of BCR-ABL transcript variations in chronic myeloid leukemia patients in cytogenetic remission

M Serpa, SS Sanabani, PE Dorliac-Llacer, M Conchon… - BMC Hematology, 2010 - Springer
… The monitoring of BCR-ABL transcript levels by real-time quantitative polymerase chain reaction
(RT-… pretreated with interferon alpha. Low levels of residual disease are associated with …