[PDF][PDF] UHRF1 is essential for proper cytoplasm architecture and function of mouse oocyte and derived embryos

上村, 修平 - 2023 - catalog.lib.kyushu-u.ac.jp
… These results suggest that Uhrf1 mat-KO pronuclei can support … that UHRF1 in oocytes is
important for the formation of … for proper regulation of proteins associated with cytoskeletal

Cellular atlas of the human ovary using morphologically guided spatial transcriptomics and single-cell sequencing

ASK Jones, DF Hannum, JH Machlin, A Tan, Q Ma… - Science …, 2024 - science.org
… Despite the ovary’s importance in fertility and endocrine health… peptidyl arginine deiminase
family, localizes to cytoplasmic lattices in mouse oocytes and has been shown to be essential

Citrullination regulates wound responses and tissue regeneration in zebrafish

N Golenberg, JM Squirrell, DA Bennin, J Rindy… - Journal of Cell …, 2020 - rupress.org
… Taken together, our results show that Padi2 is required for … -dependent enzymes,
peptidylarginine deiminases (PADs or PADIs), … By 6 hpw, the wound epithelium has already …

[HTML][HTML] Ultrastructural Evaluation of Mouse Oocytes Exposed In Vitro to Different Concentrations of the Fungicide Mancozeb

M Gatti, M Belli, M De Rubeis, MA Khalili, G Familiari… - Biology, 2023 - mdpi.com
… environmental health hazards, including female fertility. Although the dithiocarbamate …
seems to be critical for the oocyte-embryo transition, particularly for meiotic spindle formation and …

A maternal-effect Padi6 variant results in abnormal nuclear localization of DNMT1 and failure of epigenetic reprogramming and zygotic genome activation in mouse …

C Giaccari, F Cecere, L Argenziano, A Galvao… - bioRxiv, 2023 - biorxiv.org
… similar study on male fertility, but no significant difference … variant on the oocyte transcriptome,
we analysed MII oocytes … of the oocyte-derived SCMC protein PADI6 is needed for pre-…

[HTML][HTML] Acute Hypoxia Alters Extracellular Vesicle Signatures and the Brain Citrullinome of Naked Mole-Rats (Heterocephalus glaber)

S D'Alessio, H Cheng, L Eaton, I Kraev… - International Journal of …, 2022 - mdpi.com
… function were identified, including tubulin and plectin, which is a key cytoskeleton interlinking
… The role for PAD6 is mainly linked to developmental processes, including oocyte formation

Acquisition of 2C-like totipotency through defined maternal-effect factors

L Gui, Q Zhong, J Yang, J Sun, J Lu, HM Picton… - Stem Cells, 2024 - academic.oup.com
… to the de novo protein synthesis, cytoskeletal sheet formation and EGA; Padi6−/…
Peptidylarginine deiminase (PAD) 6 is essential for oocyte cytoskeletal sheet formation and female

Novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2

S Pasquero, F Gugliesi, G Griffante, V Dell'Oste… - Antiviral Research, 2022 - Elsevier
… on host-cell factors essential for viral replication, are a promising class of antiviral compounds.
Here we show that a new class of HTAs targeting peptidylarginine deiminases (PADs), a …

Losing the maternal effect gene Nlrp2 alters the ovulated mouse oocytes transcriptome and impacts histone demethylase KDM1B expression

Z Anvar, I Chakchouk, M Sharif, S Mahadevan… - 2022 - researchsquare.com
Peptidylarginine deiminase (PAD) 6 is essential for oocyte cytoskeletal sheet formation
and female fertility. Mol Cell Endocrinol 273, 25-31, doi:10.1016/j.mce.2007.05.005 (2007). …

[图书][B] PAD4 Mediated Cancer Extracellular Chromatin Network in Breast Cancer Promotes the Development and Progression of Lung Metastasis

L Shi - 2019 - search.proquest.com
PAD6 can regulate female fertility, oocyte cytoskeletal sheet formation and microtubule …
cysteine residues, PAD6 lost some of those essential active residues and is not a functional …