Biomaterials for personalized cell therapy

AL Facklam, LR Volpatti, DG Anderson - Advanced materials, 2020 - Wiley Online Library
… of stem cells remains a barrier to the translation of personalized … progress toward the
translation of personalized therapies, DOE … and therapeutic efficacy of patient-derived stem cells. …

Treatment of cystic fibrosis: from gene-to cell-based therapies

KM Allan, N Farrow, M Donnelley, A Jaffe… - Frontiers in …, 2021 - frontiersin.org
… CF therapy and advances toward their clinical translation will … fibrotic scarring in comparison
to children, with less progressed … mesenchymal and induced pluripotent stem cells (iPSCs). …

Nat1 promotes translation of specific proteins that induce differentiation of mouse embryonic stem cells

H Sugiyama, K Takahashi… - Proceedings of the …, 2017 - National Acad Sciences
… of eukaryotic translation initiation factor 4G (eIF4G), is essential for differentiation of mouse …
stem cells (mES cells). In the current study, we demonstrate that Nat1 supports the translation

Hematopoietic stem cell gene therapy for storage disease: current and new indications

A Biffi - Molecular Therapy, 2017 - cell.com
treatment modalities, hematopoietic stem cell gene therapy could potentially result in robust
therapeutic … treated patients will allow translating this promise into new medicinal products. …

… factors and microRNAs network associated with differentiation of embryonic stem cells and induced pluripotent stem cells toward cardiomyocytes: A Review

A Zare, A Salehpour, A Khoradmehr, S Bakhshalizadeh… - Life, 2023 - mdpi.com
… statistics as the inertia of cardiovascular disease therapy, and therefore, more advanced …
MiRNAs promote mRNA breakdown or impede mRNA translation to negatively control the gene …

Recent advances in treatment of coronary artery disease: role of science and technology

E Kandaswamy, L Zuo - International journal of molecular sciences, 2018 - mdpi.com
… (in age-adjusted subjects) towards the turn of the 20th century [1… been documented, which
have translated into improved patient … Stem cell therapy continues to be a promising treatment

Mesenchymal stem cell mediates cardiac repair through autocrine, paracrine and endocrine axes

C Sid-Otmane, LP Perrault, HQ Ly - Journal of Translational Medicine, 2020 - Springer
… Ischemic heart disease (IHD) due to coronary artery disease remains a … adult stem cells,
MSCs represent an interesting population that garnered increased interest for clinical translation

[HTML][HTML] Promising therapeutic strategies for mesenchymal stem cell-based cardiovascular regeneration: from cell priming to tissue engineering

ST Ji, H Kim, J Yun, JS Chung, SM Kwon - Stem cells international, 2017 - hindawi.com
therapy has been applied to treat cardiovascular disease [4]. … promising cell therapeutic
strategies for MSC therapy againsttranslate into convenient and extremely effective cell therapy […

[HTML][HTML] Stem cell-based therapy for human diseases

DM Hoang, PT Pham, TQ Bach, ATL Ngo… - … and targeted therapy, 2022 - nature.com
stem cell population and/or replenishing the cell pool toward … Since then, the translation of
basic research to preclinical … to MSC-based therapy in cardiovascular disease with the aim …

Functional dental pulp regeneration: basic research and clinical translation

Z Xie, Z Shen, P Zhan, J Yang, Q Huang… - International journal of …, 2021 - mdpi.com
therapy” of RCT for pulpal and periapical diseases, which is of great significance in dental
stem cell-based clinical translation [142]… Although efficient and safe, personalised cell therapy