Introduction There is much popular discussion on strategies to facilitate multiple orgasms in
men (ie, 100,000+ hits in Google), yet the topic has not received an objective …

Purpose: We determined whether the degree of genital malformation at birth in children with
a disorder of sex development is related to subsequent caregiver distress, specifically …

Purpose Indications that the prenatal action of testosterone in the brain is an important
determinant of gender development and improved reconstructive techniques have caused a …

Syndromes resulting in Disorders of Sex Development (DSD) are individually rare.
Historically, this fact has hindered both clinical research and the delivery of evidence-based …

Introduction Prior studies of outcomes following genitoplasty have reported high rates of
surgical complications among children with atypical genitalia. Few studies have …

Background 17β-Hydroxysteroid dehydrogenase type-3 (17βHSD-3) deficiency is a rare
cause of 46, XY disorders of sex development. The enzyme converts androstenedione to …

Introduction Hypospadias is a common congenital anomaly caused by incomplete fusion of
urethral folds. Development of the urethra and external genital system in the male fetus is an …

The purpose of this chapter is to review the presentation and management of patients
affected by conditions of abnormal sex differentiation. First, the processes of normal sex …

STUDY QUESTION What are the levels of breast development and satisfaction in women
with a Disorder/Difference of Sex Development (DSD)? SUMMARY ANSWER Compared …

Purpose: To improve treatment policy, we retrospectively evaluated the results of early
corrective genital surgery in 63 sexually ambiguous patients 14 to 38 years old. Materials …