Human leukocyte antigen (HLA) peptides derived from tumor antigens induced by inhibition of DNA methylation for development of drug-facilitated immunotherapy
B Shraibman, DM Kadosh, E Barnea… - Molecular & Cellular …, 2016 - ASBMB
… with inhibitors of methylation, such as 5-aza… DNA methyltransferases by trapping these
enzymes after its incorporation into the DNA, thus reducing methylation of newly synthesized DNA …
enzymes after its incorporation into the DNA, thus reducing methylation of newly synthesized DNA …
[HTML][HTML] A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival
PP Lee, DR Fitzpatrick, C Beard, HK Jessup, S Lehar… - Immunity, 2001 - cell.com
… To address the role of Dnmt1 and DNA methylation in T cells directly, we generated mice …
DNA methylation are essential for normal T cell homeostasis and play distinct developmental …
DNA methylation are essential for normal T cell homeostasis and play distinct developmental …
[HTML][HTML] The importance of DNA methylation in prostate cancer development
… DNA methylation, its general role in cancer and the tools available to interrogate it, we consider
the literature surrounding DNA methylation … that have reported on methylation changes in …
the literature surrounding DNA methylation … that have reported on methylation changes in …
A single CMT methyltransferase homolog is involved in CHG DNA methylation and development of Physcomitrella patens
… and gametophore development and is involved in CHG methylation as … DNA methylation
mediated by CMT has been employed early in land plant evolution to control developmental …
mediated by CMT has been employed early in land plant evolution to control developmental …
[HTML][HTML] DNA methylation and histone deacetylation in the control of gene expression: basic biochemistry to human development and disease
A El-Osta, AP Wolffe - Gene expression, 2000 - ncbi.nlm.nih.gov
… DNA methylation is a major determinant in the epigenetic silencing of genes. The … of DNA
methylation and the subsequent repression of transcription are relevant to human development …
methylation and the subsequent repression of transcription are relevant to human development …
DNA methylation pattern in human zygotes and developing embryos
H Fulka, M Mrazek, O Tepla, J Fulka - Reproduction, 2004 - rep.bioscientifica.com
We report on observations of the global methylation/demethylation pattern of both pronuclei
in human zygotes and in early embryos up to the blastocyst stage. Our results demonstrate …
in human zygotes and in early embryos up to the blastocyst stage. Our results demonstrate …
DNA methylation dynamics in health and disease
Y Bergman, H Cedar - Nature structural & molecular biology, 2013 - nature.com
… DNA methylation is an epigenetic mark that is erased in the early embryo and then re-… In
this Review, dynamics of DNA methylation during normal development in vivo are discussed, …
this Review, dynamics of DNA methylation during normal development in vivo are discussed, …
Genome-wide analysis of DNA methylation dynamics during early human development
H Okae, H Chiba, H Hiura, H Hamada, A Sato… - PLoS …, 2014 - journals.plos.org
… the increased risk of DNA methylation errors associated with … DNA methylation patterns
during early human development. … DNA methylation dynamics during early human development…
during early human development. … DNA methylation dynamics during early human development…
DNA methylation-free Arabidopsis reveals crucial roles of DNA methylation in regulating gene expression and development
L He, H Huang, M Bradai, C Zhao, Y You, J Ma… - Nature …, 2022 - nature.com
… Our findings extend prior knowledge on the importance of DNA methylation for global gene
expression and development in plants and establish a framework for the future investigation …
expression and development in plants and establish a framework for the future investigation …
[HTML][HTML] Assessing the effects of high methionine intake on DNA methylation
RA Waterland - The Journal of nutrition, 2006 - Elsevier
… locus-specific DNA methylation. This paper discusses the important role of DNA methylation
in … During prenatal and early postnatal development, when tissue-specific DNA methylation …
in … During prenatal and early postnatal development, when tissue-specific DNA methylation …