… proteins that form proton-selective ion channels. Influenza A virus A/M2 channel is the
target of the antiviral drug amantadine (and its methyl derivative rimantadine), whereas BM2 …

… very low sequence homology with the ion channels from prokaryotes and … channel proteins
can be inhibited, and thus alluded to new opportunities of using viroporins as antiviral targets. …

… This paper reviews the progress of small molecular inhibitors act as antiviral … M2 ion channel
protein inhibitors etc. Moreover, we also summarize new, recently reported potential targets …

… High-resolution structures of these targets, some in complex … Expanding our knowledge of
SARS-CoV-2 target proteins … The SARS-CoV-2 genome encodes three putative ion channels (…

… virus replication and both may serve as targets for antiviral drugs. Furthermore, we raise the
… the viral ion channel. There is no evidence that the influenza virus M2 ion channel activity is …

… antiviral agents for IV have been developed to control IV pandemics by blocking two different
targets: matrix protein 2 (M2) ion channel … HA disulfide bonds as an antiviral target herein. …

… antiviral drugs approved to treat influenza virus infections are currently limited to two targets,
the viral neuraminidase and the viral ion channel… antiviral strategies targeting these viruses. …

… The life cycle of a virus presents many potential targets for antiviral … target-specific compounds
in viral infections. One of the mechanisms is associated with the inhibition of ion channels…

… target of antiviral drugs is to block the viral replication cycle at any of these stages. Currently,
there are more than eighty antiviral … is crucial in forming ion channels in host cell membranes…

… ion channel could be effectively inhibited by amantadine and rimantadine. This indicates that
current antiviral … to the fact that ribavirin's main target of antiviral action is a cellular enzyme: …