… gene family consists of three closely related genes, PON1, … have significantly higher PON2
levels than neurons, with the loss of … Glutathione levels are identical in cells from wildtype and …

… We examined TSPO levels in a neurodegenerative transgenic mouse model of Sandhoff …
TSPO field and to inform neurotoxicity assessments and neurological disease treatments. …

… to form neurotoxic oligomers and fibers causing neuronal … induced expression of the genes
for activation of molecular … of HSP 70 to suppress the neurotoxicity caused by misfolding of …

… The environmental, genetic and epigenetic factors are … lipid peroxidation and reduced
glutathione concentrations in the … by domoic acid in mouse cerebellar granule neurons involves …

… vary in molecular weights, from domoic acid with 311 Da to … evidenced by the depletion of
intracellular glutathione. Oxidative … to compare the expression of genes affected by brevetoxin …

… by antioxidants including glutathione, metallothioneins (MTs), … kainic acid– and domoic
acid–induced apoptosis of cultured … cause hepatotoxicity and neurotoxicity much earlier than …

… Membrane transporters Nutritional regulation of cell signaling, cell growth, proliferation,
and survival Effects of nutrients on gene expression Concluding remarks and future directions …

… in ATP depletion, mitochondrial injury, amyloid β deposition and … Neurotoxic signaling
cascades initiated by ethanol … , initiating gene expression of antioxidant enzymes that protect …

… The freshwater turtle, Trachemys scripta, was utilized as a model for brevetoxin exposure in
… Brevetoxins cause acute excitotoxicity in primary cultures of rat cerebellar granule neurons. …

… effect of alamethicin and domoic acid using a larval Diptera … toxin syndrome, our human cell
model studies provide the first … neuronal cultures than could be explained from pure domoic …