Too many white cells—TAM, JMML, or something else?
A Satty, E Stieglitz, N Kucine - Hematology, 2023 - ashpublications.org
… (DS-ALL) than the general pediatric population, although this is quite rare in young infants.
… or t(8;16)(p11;p13) may have features resembling JMML; due to clinical and biological …
… or t(8;16)(p11;p13) may have features resembling JMML; due to clinical and biological …
[图书][B] Treatment failure in pediatric acute myeloid leukemia: factors associated with frequency and outcome of resistant disease and relapse.
L Karlsson - 2023 - gupea.ub.gu.se
… The aim of this paper was to characterize clinical and biological … Study by the International
Berlin-Frankfurt-Münster Study … Acute myeloid leukemia (AML) with t(7;12)(q36;p13) is …
Berlin-Frankfurt-Münster Study … Acute myeloid leukemia (AML) with t(7;12)(q36;p13) is …
Structural variants involving MLLT10 fusion are associated with adverse outcomes in pediatric acute myeloid leukemia
O Abla, RE Ries, T Triche Jr, RB Gerbing… - Blood …, 2024 - ashpublications.org
… Because of the significant heterogeneity of pediatric AML, ongoing clinical trials have … A
large International Berlin-Frankfurt-Munster Study Group (I-BFM-SG) collaborative study showed …
large International Berlin-Frankfurt-Munster Study Group (I-BFM-SG) collaborative study showed …
[HTML][HTML] The skin as an early expression of malignancies in the neonatal age: a review of the literature and a case series
V Mondì, F Piersigilli, G Salvatori, C Auriti - BioMed research …, 2015 - hindawi.com
… affected by AML M4 with t(8;16)(p11;p13). Nevertheless, … The recognition of this rare clinical
entity can be important to … , represents 4–8% of all malignant solid tumors in childhood, with …
entity can be important to … , represents 4–8% of all malignant solid tumors in childhood, with …
Significance of cytogenetics in leukemia diagnostics
TSK Wan, EKC Hui, MHL Ng - Current Genetic Medicine Reports, 2018 - Springer
… different prognoses for clinical outcome in childhood acute … translocation t(8;21)(q22;q22)
and/or inversion inv(16)(p13.… (9;20)(p11~13;q11) is rare, both in pediatric or adult ALL. As this …
and/or inversion inv(16)(p13.… (9;20)(p11~13;q11) is rare, both in pediatric or adult ALL. As this …
[HTML][HTML] Hoxa11-mediated reduction of cell migration contributes to myeloid sarcoma formation induced by cooperation of MLL/AF10 with activating KRAS mutation in …
JF Fu, CJ Wen, TH Yen, LY Shih - Neoplasia, 2022 - Elsevier
… was observed in AML with MLL-t or t(8;16)(p11;p13), and these two types … Our results support
the clinical observations that Hoxa10 … leukemia in children with acute myeloid leukemia: A …
the clinical observations that Hoxa10 … leukemia in children with acute myeloid leukemia: A …
[HTML][HTML] Rare Hematologic Malignancies and Pre-Leukemic Entities in Children and Adolescents Young Adults
A Brown, S Batra - Cancers, 2024 - mdpi.com
… We discuss the unique biology, characteristic genomic … The translocation t(8;16)(p11;p13)
results in fusion of KAT6A … these patients represent a clinically significant distinct subgroup. In …
results in fusion of KAT6A … these patients represent a clinically significant distinct subgroup. In …
Acute Myeloid Leukemia
S Adachi, A Kinoshita, D Tomizawa, T Taga… - … Disorders in Children …, 2017 - Springer
… diagnosed AML, clinical studies are conducted separately … pediatric AML study groups, which
is predictive of final outcome. … In the ongoing AML-P13 trial for childhood APL in Japan, all …
is predictive of final outcome. … In the ongoing AML-P13 trial for childhood APL in Japan, all …
[HTML][HTML] A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy
A Raymond, B Liu, H Liang, C Wei, M Guindani, Y Lu… - Oncotarget, 2014 - ncbi.nlm.nih.gov
… (AML), the most common leukemia in adults, is clinically and … recurrent and some unique
to individual leukemia, uncovering … Additionally, a subset of pediatric AML cases with a novel …
to individual leukemia, uncovering … Additionally, a subset of pediatric AML cases with a novel …
Cytogenetics of acute leukemia
NA Heerema, SC Raimondi - Neoplastic Diseases of the Blood, 2018 - Springer
… with t(8;16)(p11.2;p13.3) can present with leukemia cutis (… 8% of children; it is rarely
observed with other recurrent abnormalities such as 11q23, t(8;21)(q22;q22), or inv(16)/t(16;16)(p13.…
observed with other recurrent abnormalities such as 11q23, t(8;21)(q22;q22), or inv(16)/t(16;16)(p13.…