… spindle and is important for the cytoskeletal function22,23. … , is a member of the peptidylarginine
deiminase or PAD family. … is important for organelle positioning in immature oocytes and …

… In rheumatoid arthritis, normally cytoplasmic peptidylarginine deiminase (PAD) enzymes …
In mouse, PAD6 is observed to associate with the egg cytoskeletal sheet, which is a fibrous …

… of actin cytoskeleton were among those more accounted for cellular components (Figure
S5F). … (G) Vlnplots of expression of key genes involved in ferroptosis processes in oocytes and …

… Peptidylarginine deiminases (PAD) enzymes were initially … protein kinase C and the
cytoskeletal filament actin to activate L-… may lead to future fertility therapeutics to prevent recurrent …

… HLA regions, such as peptidylarginine deiminase (PAD), signal … Recent theory suggests that
T H17 cells are more important … antibodies, induce NET formation, and NETosis provides the …

… family of proteins called peptidylarginine deiminases (PADIs)… to exist as a regulatory measure
to impact tissue formation. … filaments to form a dense cytoskeletal structure to withstand the …

1. Abstract 1.1 English version 6 1.2 Italian version 7 2. Aim of the work 8 3. Introduction 12
3.1 Protein folding and missense mutations 13 3.2 The role of common variants in the course …

… PADs is similarly broad suggesting that substrate recognition is driven primarily by sequence
context rather than key … to rhodamine–alkyne via the formation of a triazole linker to …

… of β-carboline-derived peptidyl arginine deiminase 4 inhibitors that exhibited potent inhibition
of … The formation of a stable salt bridge with key residues Asp350 and Asp473 enabled the …

… with human recombinant peptidylarginine deiminase 2 (PAD2). … Female fertility, oocyte
cytoskeletal sheet formation, early … or formation of immune complexes plays an important role in …