… 21, in Down’s syndrome pluripotent stem cells. The XIST non-coding RNA coats … also
surmounts the major first step towards potential development of ‘chromosome therapy’. …

… have fostered a rapid clinical translation, but positive results … Coronary heart disease (CHD)
is estimated to affect near 16 … shifted towards a paracrine paradigm, where stem cells exert …

… statistics as the inertia of cardiovascular disease therapy, and therefore, more advanced …
MiRNAs promote mRNA breakdown or impede mRNA translation to negatively control the gene …

… and treatment. Early research in ischaemic heart disease has paved the way for stem cell …
Stem cell therapy has demonstrated significant improvements in cardiac function in adults …

… therapy and a potential benefit to children with OI. Encouraged by these reports, we used
IUT of fetal MSC to treat … probes against the whole male and female genome, Y-positive cells …

… for immune attack against therapeutic cells expressing a … stem cell engraftment (35) and
as therapy for children with … To investigate whether these preclinical findings translate to ..…

… Cellular therapy for cardiovascular disease heralds an … protective effects of MSCs against
hypoxic and ischemic insult [… The translation of MSC therapy to clinical cardiology requires that …

… directed toward translating these approaches to treating … , and in 2017 it was reported that
two children with R/R B-ALL … to skew CAR T cell phenotype toward a stem cell/ central memory …

… about the etiology of congenital heart disease (CHD) persist. … on translation of genomics
towards personalized healthcare. … clinical hurdles pluripotent stem cell therapy must overcome …

… toward a defined culture of hPSCs, although initially focused on eliminating feeder layers and
animal serum products to allow future clinical translation… for treating cardiovascular disease…