Brain-derived neurotrophic factor controls dopamine D3 receptor expression: therapeutic implications in Parkinson's disease

O Guillin, N Griffon, E Bezard, L Leriche, J Diaz… - European journal of …, 2003 - Elsevier
Brain-derived neurotrophic factor (BDNF) belongs to a family of proteins related to nerve
growth factor, which are responsible for neuron proliferation, survival and differentiation. A …

Meta-analysis of BDNF levels in autism

R Armeanu, M Mokkonen, B Crespi - Cellular and molecular neurobiology, 2017 - Springer
Brain-derived neurotrophic factor (BDNF) centrally mediates growth, differentiation and
survival of neurons, and the synaptic plasticity that underlies learning and memory. Recent …

Blood BDNF concentrations reflect brain-tissue BDNF levels across species

AB Klein, R Williamson, MA Santini… - International Journal …, 2011 - academic.oup.com
Brain-derived neurotrophic factor (BDNF) is involved in synaptic plasticity, neuronal
differentiation and survival of neurons. Observations of decreased serum BDNF levels in …

Role of neurotrophic factors in behavioral processes: implications for the treatment of psychiatric and neurodegenerative disorders

MC Pardon - Vitamins & Hormones, 2010 - Elsevier
Neurotrophins are important regulators of neuronal function in the developing and adult
brain and thus play a critical role in sustaining normal behavioral function. Brain-derived …

Serum brain-derived neurotrophic factor, glial-derived neurotrophic factor, nerve growth factor, and neurotrophin-3 levels in children with attention-deficit/hyperactivity …

A Bilgiç, A Toker, Ü Işık, İ Kılınç - European child & adolescent psychiatry, 2017 - Springer
It has been suggested that neurotrophins are involved in the etiopathogenesis of attention-
deficit/hyperactivity disorder (ADHD). This study aimed to investigate whether there are …

BDNF variant linked to anxiety‐related behaviors

K Hashimoto - Bioessays, 2007 - Wiley Online Library
Brain-derived neurotrophic factor (BDNF) is the most-abundant neurotrophin in the brain. In
mammals, it is synthesized as a precursor called proBDNF, which is proteolytically cleaved …

An 840 kb distant upstream enhancer is a crucial regulator of catecholamine‐dependent expression of the Bdnf gene in astrocytes

A Avarlaid, EE Esvald, I Koppel, A Parkman… - Glia, 2024 - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) plays a fundamental role in the developing and
adult nervous system, contributing to neuronal survival, differentiation, and synaptic …

Effect of antipsychotic drugs on brain‐derived neurotrophic factor expression under reduced N‐methyl‐D‐aspartate receptor activity

F Fumagalli, R Molteni, M Roceri… - Journal of …, 2003 - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) promotes a variety of neuromodulatory processes
during development as well as in adulthood. This neurotrophin has been associated with …

Shedding light into the role of BDNF in the pharmacotherapy of Parkinson's disease

F Fumagalli, G Racagni, MA Riva - The pharmacogenomics journal, 2006 - nature.com
Parkinson's disease (PD) is a chronic, neurodegenerative disease with a 1% incidence in
the population over 55 years of age. Movement impairments represent undoubtedly the …

Impact of the BDNF Val66Met polymorphism on cognition: implications for behavioral genetics

I Dincheva, CE Glatt, FS Lee - The Neuroscientist, 2012 - journals.sagepub.com
Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin growth factor
family and is implicated as a modulator of neuronal survival and differentiation, synaptic …