… survival, time to death, or weight loss (Figure S5). These data suggest that the GABA shunt
increases parasite fitness but that this pathway is not essential … apicoplast fatty acid synthesis. …

… apicoplast and the unique fatty acid synthetic pathways operational in this organelle has
highlighted that the parasite synthesizes prokaryotic-like lipids that are essential for its survival. …

… critical role in the inheritance of apicoplast and the survival of … been identified to be important
for apicoplast biogenesis in T. … apicoplast and causes the typical delayed death of parasites. …

… species are important enteric pathogens [2], and Toxoplasma gondii is … organelle called the
apicoplast, which is essential for their … with this organelle, including the synthesis of fatty acid, …

… why the apicoplast is essential for the parasite's survival. This … The type II fatty acid synthesis
(FASII) pathway is the best … from Toxoplasma gondii localizes to both the apicoplast and …

… such as malaria and Toxoplasma gondii gave us new insight … By contrast, apicoplast fatty
acid biosynthesis is essential in T… Remarkably, these ‘apicoplast-minus’ parasites survive and …

… The apicoplast appears to be indispensable to the parasites, … two essential biosynthetic
pathways, the fatty acid synthesis … to the apicoplast are known to be essential for survival of the …

… of the apicomplexan Toxoplasma gondii to genetic manipulation … , the apicoplast is still
necessary for parasite survival as it is the site of essential metabolic pathways including fatty acid, …

… Not only is the pathway not essential for host survival in the … and development of fatty acid
synthesis as an important drug … and Toxoplasma gondii carry a relict plastid, or apicoplast, [10] …