Exercise-Mediated Protection against Air Pollution-Induced Immune Damage: Mechanisms, Challenges, and Future Directions

X Jin, Y Chen, B Xu, H Tian - Biology, 2024 - mdpi.com
… the evidence from humans, mice, and cell experiments on the … of immune health: inflammatory
response, oxidative stress, and … NO 2 also induced an imbalance in the ratio of Th1/Th2

Convergence of air pollutant-induced redox-sensitive signals in the dendritic cells contributes to asthma pathogenesis

N Li, N Buglak - Toxicology Letters, 2015 - Elsevier
mice were much more susceptible to the adjuvant effect of … several cytokines involved in
allergic and inflammatory responses (ie… Not only can PM alter Th1/Th2 balance, it has also been …

Identification and validation of metformin protects against PM2. 5-induced macrophages cytotoxicity by targeting toll like receptor pathway

Y Shi, JW Batibawa, M Maiga, B Sun, Y Li, J Duan… - Chemosphere, 2020 - Elsevier
… PM 2.5 (10 μg/mouse) were instilled intratracheally with or … and Tlr6 at 24 h but Tlr2 was
not affected by PM 2.5 (Fig. 4A). … (TRAP) induced brain inflammatory responses are TLR4-…

Air pollution and the airways: lessons from a century of human urbanization

J Goossens, AC Jonckheere, LJ Dupont, DMA Bullens - Atmosphere, 2021 - mdpi.com
… effect on the airways, particulate matter is supposed to have … the induction of oxidative stress
and inflammatory responses … ozone-induced airway hyperreactivity in C57BL/6 mice [39]. …

The effects of air pollutants exposure on the transmission and severity of invasive infection caused by an opportunistic pathogen Streptococcus pyogenes

Y Zhi, X Chen, G Cao, F Chen, HS Seo, F Li - Environmental Pollution, 2022 - Elsevier
… (DEP), a significant constituent of particulate matter (PM), are … during GAS M1 strain infection
in mice. Thus, we characterized … an inflammatory response by mediating MAPK signaling …

PM2.5 downregulates miR-194-3p and accelerates apoptosis in cigarette-inflamed bronchial epithelium by targeting death-associated protein kinase 1

T Zhou, Y Zhong, Y Hu, C Sun, Y Wang… - International journal of …, 2018 - Taylor & Francis
Fine particulate matter (PM 2.5 ) is an aggravating risk factor … lung inflammation and oxidative
stress in COPD mice, but the … the inflammatory response involved in PM 2.5 -induced lung …

Histidine ameliorates elastase-and lipopolysaccharide-induced lung inflammation by inhibiting the activation of the NLRP3 inflammasome

Q Tian, M Xu, B He - Acta Biochimica et Biophysica Sinica, 2021 - academic.oup.com
… To further explore the role of histidine in E/LPS-induced mice, … the inflammatory responses
in E/LPS-induced COPD mice. … is involved in cigarette smoking, fine particulate matter (PM)-…

Lung dendritic cells in respiratory viral infection and asthma: from protection to immunopathology

BN Lambrecht, H Hammad - Annual review of immunology, 2012 - annualreviews.org
… example of lung inflammatory responses in which DCs play an important role, not … in mice,
the direct involvement of TLRs on DCs has never been shown. For ambient particulate matter, …

[HTML][HTML] The Impact of PM2.5 on the Host Defense of Respiratory System

L Yang, C Li, X Tang - Frontiers in cell and developmental biology, 2020 - frontiersin.org
… The harm of fine particulate matter (PM 2.5 ) to public health is the focus of attention around
… monocytogenes) in rats. Another research discovered that the colony-forming units (CFUs) …

Luteolin attenuates PM2. 5-induced inflammatory responses by augmenting HO-1 and JAK-STAT expression in murine alveolar macrophages

WC Hsieh, CY Lai, HW Lin, DG Tu… - Food and Agricultural …, 2022 - Taylor & Francis
involved mechanisms and possible treatments of ambientParticulate matter includes PM10,
which can pass through the … , have also been detected in mice myocardial tissue upon co-…