… The life cycle of a virus presents many potential targets for antiviral … target-specific compounds
in viral infections. One of the mechanisms is associated with the inhibition of ion channels…

… target of antiviral drugs is to block the viral replication cycle at any of these stages. Currently,
there are more than eighty antiviral … is crucial in forming ion channels in host cell membranes…

… of antiviral drugs are currently available: the M2 ion channel … develop the next generation of
antiviral drugs that are active against … on the amount of time the drug is exposed to the target. …

… ion channel could be effectively inhibited by amantadine and rimantadine. This indicates that
current antiviral … to the fact that ribavirin's main target of antiviral action is a cellular enzyme: …

… that ion channel activity correlated well with the virus growth. The strong E-protein ion channel
… Hence, inhibitor target to E-protein process can help to prevent virus production. In this …

… proteins that form proton-selective ion channels. Influenza A virus A/M2 channel is the
target of the antiviral drug amantadine (and its methyl derivative rimantadine), whereas BM2 …

… As a search for novel drug targets among virus-encoded ion channels, we looked in the
genome … In support of an antiviral effect, amantadine was recently shown to inhibit SARS-CoV-2 …

… antiviral agents for IV have been developed to control IV pandemics by blocking two different
targets: matrix protein 2 (M2) ion channel … HA disulfide bonds as an antiviral target herein. …

… ion channel formed by p7 or the membrane-active protein NS4B, represent alternative targets
for antiviral … of two viral enzymes that are targets for antiviral therapy: the protease NS3-4A …

… do not require specific antiviral therapy. The currently available antiviral drugs target 3 main
groups … Drugs for the treatment of influenza inhibit the ion channel M 2 protein or the enzyme …