Investigating the neuroprotective and anti-epileptogenic mechanisms of inducible nitric oxide synthase and Src family kinase/Fyn inhibitors in experimental models of …

S Sharma - 2019 - search.proquest.com
… resistant to kainate-induced neurotoxicity. It also describes the … Most of the genes responsible
for human diseases are also … After an optimum level of glutathione depletion has reached, …

Mechanistic evaluation of ursolic acid against rotenone induced Parkinson's disease–emphasizing the role of mitochondrial biogenesis

V Peshattiwar, S Muke, A Kaikini, S Bagle, V Dighe… - Brain Research …, 2020 - Elsevier
… influenced by both genetic defect and environmental factors. … potential of UA against
neurotoxicity induced by rotenone in … the bilateral intranigral infusion model is utilized in order to …

[引用][C] Dietary Neurotoxins

AD Neurotoxins

[HTML][HTML] Nrf2/ARE pathway modulation by dietary energy regulation in neurological disorders

AR Vasconcelos, NB Dos Santos, C Scavone… - Frontiers in …, 2019 - frontiersin.org
… can produce an array of neurotoxic factors, including proteases, … Part of the effects associated
with Nrf2 deficiency may be related … Many genes involved in glutathione metabolism are …

Nanomolar Methylmercury: Neurodevelopmental Effects in Human Neural Stem Cells and Zebrafish Embryo

M Torres-Ruiz, M de Alba, AC Portilla… - Available at SSRN … - papers.ssrn.com
… in low doses of MeHg neurotoxicity, we have examined 117 … To analyze q-RT-PCR data
two replicates for each gene of … neurotoxic effects on the developing zebrafish embryo model. …

Drug transport in the brain

V Sangha, EI Williams, PT Ronaldson… - … and role in drug …, 2022 - Wiley Online Library
… disorders such as cerebral folate deficiency, multiple sclerosis, … at the gene level in an in vitro
rat BBB model comprised of … Oatp2b1 may be involved in neurotoxicity due to their ability to …

[PDF][PDF] 16GLETXIV

VC Moser, M Aschner, RJ Richardson, MA Philbert - drjaberjavidi.ir
neurotoxicity and the effects of systemic toxicity on the NS. … Finally, the questions surround
ing domoic acid poisoning and … results in transcriptional repression of the gene. In histones, …

[HTML][HTML] Glutamate cysteine ligase—modulatory subunit knockout mouse shows normal insulin sensitivity but reduced liver glycogen storage

S Lavoie, P Steullet, A Kulak, F Preitner, KQ Do… - Frontiers in …, 2016 - frontiersin.org
… Deficits in glutathione, a major regulator of reactive oxygen … Therefore, understanding the
impact of a chronic glutathione … A valuable model to study the effect of a chronic GSH deficit …

ABC family transporters

X Liu - Drug transporters in drug disposition, effects and …, 2019 - Springer
gene cluster on chromosome 17q24 and are characterized by a strikingly high, mutual amino
acid … substrates and their conjugates with glucuronic acid, glutathione, and sulfate, most of …

[PDF][PDF] The role of PSA-NCAM in the survival of retinal ganglion cells

N Lobanovskaya - 2020 - core.ac.uk
… a constitutive deficiency in ST8SiaII, ST8SiaIV or NCAM genes. … -induced neurotoxicity
in the retina. Mol Brain 2013;6:34. … by kainic acid and domoic acid. Nat Toxins 1998;6:153–158. …