Respiratory cerebrospinal fluid flow is driven by the thoracic and lumbar spinal pressures

RA Lloyd, JE Butler, SC Gandevia, IK Ball… - The Journal of …, 2020 - Wiley Online Library
… used to record CSF and blood flow, while healthy subjects (5:5 … intrathoracic pressures,
epidural blood flow into the spinal … drive respiratory-related CSF flow in healthy human subjects, …

[HTML][HTML] The HDL from septic-ARDS patients with composition changes exacerbates pulmonary endothelial dysfunction and acute lung injury induced by cecal ligation …

L Yang, S Liu, S Han, Y Hu, Z Wu, X Shi, B Pang… - Respiratory …, 2020 - Springer
… and paired adult healthy subjects (volunteers) without chronic … age and sex-matched healthy
controls were collected (Table 1 … Briefly, the lung was perfused, lavaged and cut into small …

Improved velocity‐selective‐inversion arterial spin labeling for cerebral blood flow mapping with 3D acquisition

D Liu, F Xu, W Li, PC van Zijl, DD Lin… - Magnetic resonance in …, 2020 - Wiley Online Library
… FT-VSI ASL with whole-brain coverage on two healthy volunteers and a brain tumor patient.
… physiologic noise such as cardiac pulsation and respiratory cycles. Briefly, the systematic …

[HTML][HTML] Simulating Multi-Scale Pulmonary Vascular Function by Coupling Computational Fluid Dynamics With an Anatomic Network Model

BS Ebrahimi, H Kumar, MH Tawhai… - Frontiers in Network …, 2022 - frontiersin.org
… Here we present a multi-scale model that incorporates the 3-dimensional (3D) complexities
of pulmonary blood flow in the major vessels, coupled to an anatomically-based vascular …

A dynamic model of the body gas stores for carbon dioxide, oxygen, and inert gases that incorporates circulatory transport delays to and from the lung

SRM Magor-Elliott, CJ Fullerton… - Journal of Applied …, 2021 - journals.physiology.org
… to insert pulmonary artery catheters into healthy volunteers for … the lung exchange with the
atmosphere via pulmonary ventilation and with the rest of the body via pulmonary blood flow. …

Targeting HIF2α-ARNT hetero-dimerisation as a novel therapeutic strategy for pulmonary arterial hypertension

D Macias, S Moore, A Crosby… - … Respiratory Journal, 2021 - Eur Respiratory Soc
… Regional lung vasoconstriction stimulates a dynamic shift in perfusion to aid … healthy
volunteers. Mononuclear cells were isolated from 60 mL of venous blood by Ficoll density gradient

The ex vivo perfused human lung is resistant to injury by high-dose S. pneumoniae bacteremia

JT Ross, N Nesseler, A Leligdowicz… - … of Physiology-Lung …, 2020 - journals.physiology.org
lung from injury in bacteremia have not been identified. We simulated bacteremia by adding
Streptococcus pneumoniae to the perfusate of the ex vivo perfused human lunghuman lung

[HTML][HTML] … : functional evaluation of microvascular damage in connective tissue diseases. is there evidence of correlations with organ involvement, such as pulmonary …

B Ruaro, C Bruni, B Wade, E Baratella… - Frontiers in …, 2021 - frontiersin.org
healthy subjects (HS). Moreover, it has been demonstrated that LASCA is a safe technique
also able to monitor digital ulcer perfusion … tests in the evaluation of perfusion in SSc patients. …

Congenital heart disease-associated pulmonary dysplasia and its underlying mechanisms

DB Li, XX Xu, YQ Hu, Q Cui, YY Xiao… - … of Physiology-Lung …, 2023 - journals.physiology.org
pulmonary blood flow modulates postnatal lung development. Moreover, although a clinical
study of adult patients with congenital pulmonary … smaller lungs than healthy controls (11), …

[HTML][HTML] Insights into cerebral tissue-specific response to respiratory challenges at 7T: evidence for combined blood flow and CO2-mediated effects

AA Champagne, AA Bhogal - Frontiers in physiology, 2021 - frontiersin.org
… Blood Oxygen Level Dependent (BOLD) datasets were acquired at 7T in nine healthy
subjects throughout BLOCK- and RAMP-HC paradigms. In a subset of seven participants, a …