[HTML][HTML] mRNA vaccines for infectious diseases: principles, delivery and clinical translation
N Chaudhary, D Weissman… - Nature reviews Drug …, 2021 - nature.com
… We also overview the pipeline of mRNA vaccines against various infectious disease … adults,
children, elderly people and pregnant people. VAED, vaccine-associated enhanced disease. …
children, elderly people and pregnant people. VAED, vaccine-associated enhanced disease. …
Cardiac cell therapy: where we've been, where we are, and where we should be headed
K Malliaras, E Marban - British medical bulletin, 2011 - academic.oup.com
… (v) The beneficial effects of adult stem cell therapy are … of poorly-retained cells translate to
measurable clinical benefit, … Cardiovascular disease remains the leading cause of death and …
measurable clinical benefit, … Cardiovascular disease remains the leading cause of death and …
[HTML][HTML] Mesenchymal stem cell secretome as an emerging cell-free alternative for improving wound repair
… The use of mesenchymal stem cells (MSC) for the treatment … However, the broad translation
of cell therapies into clinical … towards the promising therapeutic potential of these cells [27]. …
of cell therapies into clinical … towards the promising therapeutic potential of these cells [27]. …
Human induced pluripotent stem cell–derived cardiomyocytes: insights into molecular, cellular, and functional phenotypes
… has enabled the modeling of human cardiovascular disease phenotypes, drug screening, …
that could be translated into revolutionary diagnostic and therapeutic modalities for individual …
that could be translated into revolutionary diagnostic and therapeutic modalities for individual …
[HTML][HTML] Potential role of exosomes in mending a broken heart: nanoshuttles propelling future clinical therapeutics forward
… a diagnostic marker for cardiovascular disease post-myocardial … translated into practice as
transplantation of stem cells has … cardiac cell therapy due to its capacity to differentiate toward …
transplantation of stem cells has … cardiac cell therapy due to its capacity to differentiate toward …
Therapeutic potential of mesenchymal stem cell-derived microvesicles
L Biancone, S Bruno, MC Deregibus… - Nephrology Dialysis …, 2012 - academic.oup.com
… mesenchymal stem cells have the potential to be exploited in novel therapeutic approaches
… , after fusion with target cells, the transferred mRNA is translated into protein by the recipient …
… , after fusion with target cells, the transferred mRNA is translated into protein by the recipient …
The advancing field of cell‐based therapy: insights and lessons from clinical trials
KS Telukuntla, VY Suncion, IH Schulman… - Journal of the …, 2013 - Am Heart Assoc
… can be translated to subpopulations of BM‐MNCs as well as other stem cells that express the
… enhanced MI size reduction and restored diastolic and systolic function toward normal after …
… enhanced MI size reduction and restored diastolic and systolic function toward normal after …
[HTML][HTML] Myocardial regeneration protocols towards the routine clinical scenario: An unseemly path from bench to bedside
… remuscularization and its hard-to-accomplish translation from bench to bedside, has been
… so-called stem cell therapy did not contain actual stem cells with cardiac remuscularization …
… so-called stem cell therapy did not contain actual stem cells with cardiac remuscularization …
Clinical development of CAR T cells—challenges and opportunities in translating innovative treatment concepts
J Hartmann, M Schüßler‐Lenz, A Bondanza… - EMBO molecular …, 2017 - embopress.org
… T cell therapy appears to be especially active against B-cell … be offered allogeneic
hematopoietic stem cell transplantation (… acute lymphoblastic leukaemia in children and young …
hematopoietic stem cell transplantation (… acute lymphoblastic leukaemia in children and young …
[HTML][HTML] Hypoxia-inducible factors: cancer progression and clinical translation
EE Wicks, GL Semenza - The Journal of clinical …, 2022 - Am Soc Clin Investig
… that mediate angiogenesis, cancer stem cell specification, cell motility, epithelial-mesenchymal …
in response to ischemic cardiovascular disease (8), and treatment of mice with the HIF …
in response to ischemic cardiovascular disease (8), and treatment of mice with the HIF …