Use of erlotinib or gefitinib as initial therapy in advanced NSCLC

GR Oxnard, VA Miller - Oncology, 2010 - search.proquest.com
… [9] An important feature of initial studies of erlotinib efficacy was that while the overall … from
patients demonstrating sensitivity to erlotinib and gefitinib, with nucleotide sequencing of their …

Erlotinib-guided self-assembled trifunctional click nanotheranostics for distinguishing druggable mutations and synergistic therapy of nonsmall cell lung cancer

Y Gao, H Zhang, Y Zhang, T Lv, L Zhang… - Molecular …, 2018 - ACS Publications
… In the present study, we utilized … erlotinib. The CE7Ns could distinguish NSCLC subtype
PC-9 cells (EGFR E746-A750 deletion, erlotinib-sensitive) from A549 (EGFR wild-type, erlotinib-…

Treatment of advanced non–small-cell lung cancer with epidermal growth factor receptor (EGFR) mutation or ALK gene rearrangement: results of an international …

C Gridelli, F De Marinis, F Cappuzzo, M Di Maio… - Clinical lung cancer, 2014 - Elsevier
… , erlotinib, or afatinib) can be used (when available) until further data from comparative studies
are … but not by the FDA; erlotinib and afatinib are approved by both agencies. Gefitinib and …

… deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non–small cell lung cancer patients treated with gefitinib or erlotinib

DM Jackman, BY Yeap, LV Sequist, N Lindeman… - Clinical Cancer …, 2006 - AACR
… with gefitinib or erlotinib from January 2001 to March 2005 were included in this study. Those
… The patients included in this study represent all of the patients from our institution who met …

Should the concomitant use of erlotinib and acid-reducing agents be avoided? The drug interaction between erlotinib and acid-reducing agents

S Duong, M Leung - Journal of Oncology Pharmacy Practice, 2011 - journals.sagepub.com
… for erlotinib reports a drug interaction between erlotinib and PPIs or H2RAs.The solubility of
erlotinib is … Comparative study with ranitidine and cimetidine on gastric secretion in normal …

Comparative clinical and economic outcomes of treatments for refractory non-small cell lung cancer (NSCLC)

JJ Carlson, C Reyes, N Oestreicher, D Lubeck… - Lung cancer, 2008 - Elsevier
… , the treatment benefits of erlotinib, docetaxel, and … comparative value in the US healthcare
setting is unclear. The objective of this study was to evaluate the cost-effectiveness of erlotinib

[HTML][HTML] Differential expression of biomarkers in lung adenocarcinoma: a comparative study between smokers and never-smokers

T Dutu, S Michiels, P Fouret, F Penault-Llorca… - Annals of oncology, 2005 - Elsevier
… However, recently, two important studies have suggested that EGFR expression evaluated
by immunohistochemistry can be associated with gefitinib [15] and erlotinib [16] sensitivity. On …

Repeat biopsy procedures and T790M rates after afatinib, gefitinib, or erlotinib therapy in patients with lung cancer

K Lee, Y Kim, HA Jung, SH Lee, JS Ahn, MJ Ahn… - Lung cancer, 2019 - Elsevier
… Therefore, our study could not include any … , our study is the first comparative analysis for
T790 M mutation rates as a resistance mechanism between afatinib and gefitinib or erlotinib. …

Coexpression of EGFR and HER-2 in pancreatic ductal adenocarcinoma: a comparative study using immunohistochemistry correlated with gene amplification by …

J Dancer, H Takei, JY Ro… - Oncology …, 2007 - spandidos-publications.com
… 25 Blaszkowsky LS, Kulke KH and Ryan DP: A phase II study of erlotinib in combination with
… Moore MJ, Goldstein D and Hamm J: Erlotinib plus gemcitabine compared to gemcitabine …

Erlotinib loaded chitosan nanoparticles: Formulation, physicochemical characterization and cytotoxic potential

P Pandey, K Dua, H Dureja - International journal of biological …, 2019 - Elsevier
study was to prepare and evaluate erlotinib loaded chitosan nanoparticles for their anticancer
potential. Also, to study the … Erlotinib loaded chitosan nanoparticles were prepared by ionic …