[HTML][HTML] Engineering cGAS-agonistic oligonucleotides as therapeutics and vaccine adjuvants for cancer immunotherapy
… stranded DNA (ssDNA), we identified Svg3 as a potent cGAS agonist for versatile applications
in combination cancer immunotherapy (… Svg3 was easily synthesized on automated DNA …
in combination cancer immunotherapy (… Svg3 was easily synthesized on automated DNA …
[HTML][HTML] CpG-C ODN M362 as an immunoadjuvant for HBV therapeutic vaccine reverses the systemic tolerance against HBV
H Zhao, Q Han, A Yang, Y Wang, G Wang… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
… Oligodeoxynucleotides (ODNs) containing class C … for the immunotherapeutic strategy against
CHB, since CpG-C … we demonstrated that CpG M362 (CpG-C ODN) as an adjuvant in anti-…
CHB, since CpG-C … we demonstrated that CpG M362 (CpG-C ODN) as an adjuvant in anti-…
Vaccine nanodiscs plus polyICLC elicit robust CD8+ T cell responses in mice and non-human primates
AH Najafabadi, ZIN Abadi, ME Aikins, KE Foulds… - Journal of Controlled …, 2021 - Elsevier
… nanoparticles designed for cancer immunotherapy. Here, we … acid-based adjuvants, including
CpG DNA oligonucleotides (… CpG and polyICLC, we sought to identify an ideal adjuvant to …
CpG DNA oligonucleotides (… CpG and polyICLC, we sought to identify an ideal adjuvant to …
Targeting dendritic cells in lymph node with an antigen peptide-based nanovaccine for cancer immunotherapy
… alone or encapsulated with CpG oligodeoxynucleotide as a … T cells without adjuvant
stimulation because of their already … Splenocytes were isolated from the spleens of these animals …
stimulation because of their already … Splenocytes were isolated from the spleens of these animals …
Toll‐like receptors: The role in bladder cancer development, progression and immunotherapy
S Ohadian Moghadam… - Scandinavian journal of …, 2019 - Wiley Online Library
… Based upon sequence homologies, the vertebrate TLRs are grouped into … DNA in short
oligonucleotides form). Intravesical … kb DNA fragments presented the maximum adjuvant activity …
oligonucleotides form). Intravesical … kb DNA fragments presented the maximum adjuvant activity …
Functionalized chitosan as a promising platform for cancer immunotherapy: A review
X Liang, M Mu, R Fan, B Zou, G Guo - Carbohydrate polymers, 2022 - Elsevier
… CpG is a nucleic acid-based immune adjuvant that … The CS/DNA complex was obtained by
adding plasmid DNA (pDNA) to the … CpG oligodeoxynucleotides (ODNs) interact with TLR-9 to …
adding plasmid DNA (pDNA) to the … CpG oligodeoxynucleotides (ODNs) interact with TLR-9 to …
IL-4Rα aptamer-liposome-CpG oligodeoxynucleotides suppress tumour growth by targeting the tumour microenvironment
YJ Liu, XQ Dou, F Wang, J Zhang, XL Wang… - Journal of drug …, 2017 - Taylor & Francis
… Thus, CpG ODN has been used as a new vaccine adjuvant and is widely used in immunotherapy.
A … All procedures involving animals were approved by the Institute of Animal Care and …
A … All procedures involving animals were approved by the Institute of Animal Care and …
Polyethylenimine-mediated CpG oligodeoxynucleotide delivery stimulates bifurcated cytokine induction
T Cheng, J Miao, D Kai, H Zhang - ACS Biomaterials Science & …, 2018 - ACS Publications
… , CpG ODNs have attracted considerable interest as immunotherapeutic agents or adjuvants
for … delivery of DNA, while its role in regulating the function of DNA has rarely been reported. …
for … delivery of DNA, while its role in regulating the function of DNA has rarely been reported. …
Investigation of peanut oral immunotherapy with CpG/peanut nanoparticles in a murine model of peanut allergy
… to standard guidelines for the care and use of animals. … The concept of including CpG
oligonucleotides or TLR … to enhance CpG adjuvant activity.42, 43 However, in our model CpG …
oligonucleotides or TLR … to enhance CpG adjuvant activity.42, 43 However, in our model CpG …
[HTML][HTML] CpG-based immunotherapy impairs antitumor activity of BRAF inhibitors in a B-cell-dependent manner
L Huang, Z Wang, C Liu, C Xu, RM Mbofung… - Oncogene, 2017 - nature.com
… microbial genomes but rare in vertebrate genomes, and thus … showed that using CpG as the
vaccine adjuvant impaired the … B cells in response to CpG-A and CpG-B oligonucleotides. J …
vaccine adjuvant impaired the … B cells in response to CpG-A and CpG-B oligonucleotides. J …