… modulation, we also look at ongoing clinical studies aimed at blocking proinflammatory
cytokines; transfer of immunosuppressive … to increase NK IFN-γ secretion, high IL-6 levels also …

… A modulation of cytokines and oxidative stress appears … administration of corticosteroids and
other immunosuppressants. … Among the biochemical mediators of pulmonary fibrosis, TGFβ …

… not treated with MSCs, suggesting the T-cell modulation … to reduce the level of several
cytokines, such as IL-1, IL-2, IL-… corticosteroids or other immunosuppressants, which patients …

… of care remains corticosteroids either with or without a second immunosuppressive agent
(1)… of the presence of Th2 cytokines as compared with IFN-γ is the finding that IFN-γ levels are …

… IL-4 is another cytokine involved in the development of PF. It … Plant extracts have shown
to modulate various fibrotic … -α, TGF-β, IFN-γ, interleukins and endothelin-1). They also …

… Hence, treatment with IFN-γ may be effective in pathological … to Th2 cytokine patterns since
leukocyte cultures from these … It modulates some inflammatory parameters which have an …

… Initially, corticosteroids and immunosuppressants were used to treat IPF … treatment
guidelines for IPF strongly recommended against use of corticosteroids and immunosuppressants …

… homologue) proteins, which modulate the transcription of target … inhibited by the T H 1-associated
cytokines IFN-γ and IL-12, … , such as corticosteroids, immunosuppressive or cytotoxic …

… , in addition to modulation from other cytokine signal inputs, … cytokine signature, including
the upregulation of IFN-γ, the … Systemic corticosteroids are associated with substantial side …

… of genes encoding for cytokines (interleukin [IL]-1 α, tumor … that patients with IPF should not
be treated with corticosteroid … in 330 patients with IPF, randomized 1:1 to receive IFN-γ 200 μg …