… complete resistance to M2 ion channel inhibitors, exacerbated by … Conclusion: Antiviral drugs
are crucial for controlling … The existing antivirals target the ion-channel activity of M2 or the …

… do not require specific antiviral therapy. The currently available antiviral drugs target 3 main
groups … Drugs for the treatment of influenza inhibit the ion channel M 2 protein or the enzyme …

… as to enable virions to reach their target cells and to depart from … ion channel The adamantanes,
amantadine and rimantadine, exert their antiviral activity by blocking the M2 ion channel…

… GIRK1 (Kcnj3) is also a predicted target of miR-221/222, but we were not able to induce
a protein reduction of this ion channel by transfection of HL-1 cells with miR-221. But further …

… -receptor binding as an antiviral target, the multivalent nature … virus to its target cell: (i) an
antiviral compound binding to the HA … Activation of the M2 ion channel below pH 6 is caused by …

… antigen) molecules are the targets of allospecific cytolytic T … necessary for the interaction
between antiviral CTL and virus-… as human target cells, as they are suitable targets and are …

… within the therapeutic target proteins M2 ion channel protein and … The M2 ion channel protein
of A(H1N1)pdm09 viruses is … occurrence and spread of antiviral resistant influenza viruses …

… pathways potential therapeutic targets for antiviral drugs. … Ion channel proteins are found in
all kingdoms of life, and … their own ion channels to subvert the host cell's normal ion gradients …

… inhibitors of the viral M2 ion channel protein (amantadine and … of antiviral drugs highlights
the need for additional antiviral … targeted for the development of antiviral drugs. We focused on …

… Theoretically, mammalian ion channel receptors are also targets of the drug. However, at …
The plethora of biological targets of ivermectin have led researchers to study the antiviral …