Semaglutide for obesity: four STEPs forward, but more to come
DH Ryan - The Lancet Diabetes & Endocrinology, 2021 - thelancet.com
… Semaglutide 2·4 mg once weekly, an anti-obesity medication now submitted to regulators
across … Semaglutide effects on cardiovascular outcomes in people with overweight or obesity (…
across … Semaglutide effects on cardiovascular outcomes in people with overweight or obesity (…
[PDF][PDF] Semaglutide: The first anti-obesity agent shown to decrease cardiovascular events
MD Nasser Mikhailand, S Wali - diabeticjournals.net
… semaglutide as the first anti-obesity drug shown to decrease CV events in subjects with
obesity and prevalent CV … The mechanisms whereby semaglutide decreased CV outcomes are …
obesity and prevalent CV … The mechanisms whereby semaglutide decreased CV outcomes are …
Once‐weekly semaglutide reduces the risk of cardiovascular events in people with type 2 diabetes and polyvascular disease: A post hoc analysis
O Kobo, MA Cavender, TJ Jensen… - Diabetes, Obesity …, 2024 - Wiley Online Library
… OW semaglutide compared with placebo was associated with a consistent reduction in CV
outcomes … those without vascular disease, and a 3.5 times greater risk of expanded composite …
outcomes … those without vascular disease, and a 3.5 times greater risk of expanded composite …
Effect of the glucagon-like peptide-1 receptor agonists semaglutide and liraglutide on kidney outcomes in patients with type 2 diabetes: pooled analysis of SUSTAIN 6 …
… Secondary kidney outcomes in these cardiovascular outcome … of semaglutide in SUSTAIN
6 and liraglutide in LEADER, compared with placebo, on clinically important kidney outcomes, …
6 and liraglutide in LEADER, compared with placebo, on clinically important kidney outcomes, …
The antiobesity effect and safety of GLP-1 receptor agonist in overweight/obese patients without diabetes: a systematic review and meta-analysis
X Guo, Z Zhou, X Lyu, H Xu, H Zhu… - Hormone and …, 2022 - thieme-connect.com
… semaglutide. Therefore, the aim of our study was to first evaluate the antiobesity effect of
semaglutide … , exenatide and semaglutide in the overweight/obese without diabetes in terms of …
semaglutide … , exenatide and semaglutide in the overweight/obese without diabetes in terms of …
Cardiovascular outcomes trials for weight loss interventions: another tool for cardiovascular prevention?
IJ Neeland, DK McGuire, N Sattar - Circulation, 2021 - Am Heart Assoc
… in Patients With Overweight or Obesity) with semaglutide 2.4 mg SQ … not clear whether these
trials will demonstrate improved cardiovascular outcomes, given the potential for an obesity …
trials will demonstrate improved cardiovascular outcomes, given the potential for an obesity …
Effect of semaglutide on coronary atherosclerosis progression in patients with type II diabetes: rationale and design of the semaglutide treatment on coronary …
… derived outcomes from liraglutide effect and action in diabetes: evaluation … cardiovascular
outcome results and semaglutide and cardiovascular outcomes in patients with type 2 diabetic …
outcome results and semaglutide and cardiovascular outcomes in patients with type 2 diabetic …
Cardiovascular outcomes trials with glucagon‐like peptide‐1 receptor agonists: a comparison of study designs, populations and results
KM Pantalone, K Munir, CM Hasenour… - Diabetes, Obesity …, 2020 - Wiley Online Library
… Like SUSTAIN-6, PIONEER 6 was designed to exclude an 80% excess in CV risk for oral
semaglutide compared with placebo, with an upper limit of the two-sided 95% CI not exceeding …
semaglutide compared with placebo, with an upper limit of the two-sided 95% CI not exceeding …
Safety and tolerability of semaglutide across the SUSTAIN and PIONEER phase IIIa clinical trial programmes
VR Aroda, U Erhan, P Jelnes, JJ Meier… - Diabetes, Obesity …, 2023 - Wiley Online Library
… Fatal AE incidence was similar between semaglutide and … adverse cardiovascular events
with subcutaneous semaglutide … Cardiovascular outcomes for patients at high cardiovascular …
with subcutaneous semaglutide … Cardiovascular outcomes for patients at high cardiovascular …
Impact of microvascular disease on cardiovascular outcomes in type 2 diabetes: results from the LEADER and SUSTAIN 6 clinical trials
S Verma, SC Bain, JB Honore… - Diabetes, Obesity …, 2020 - Wiley Online Library
… and semaglutide consistently reduced major CV outcomes in patients with and without …
the impact of microvascular disease in type 2 diabetes on CV risk, and this study represents an …
the impact of microvascular disease in type 2 diabetes on CV risk, and this study represents an …