… The potential of SOCS proteins as therapeutic targets in cancer (which is outside the scope
… Approach in viral therapy SOCS and PIAS could serve as alternative therapeutic targets in …

… Thus, understanding which cytokines play a pivotal role in the disease process can suggest
potential therapeutic targets. A number of cytokines have been therapeutically targeted with …

… In the present review, we examined the roles of circulating cytokines and cytokines in CSF
… such cytokines as therapeutic targets. It has been well documented that circulating cytokines …

… IL-6 is a multifunctional inflammatory cytokine produced by Kupffer cells in the liver in …
cytokine produced mainly by Kupffer cells and other immune cells and is an essential cytokine for …

… Tumor cells exploit their microenvironment by releasing cytokines and growth factors to
activate normal, quiescent cells around them and initiate a cascade of events that quickly …

… We hypothesize that IL-4 and IL-13 may constitute potential therapeutic targets as they
represent two of the main mediators of type 2 responses and pro-fibrotic activity, that play an …

… limited to supportive care, intensivists have directed their efforts towards understanding the
pathophysiology of ARDS in order to identify therapeutic targets that may improve outcome. …

… of pro-inflammatory cytokines and chemokines that result … Because pro-inflammatory
cytokines derived from adipocytes … the release of inflammatory cytokines from adipose tissue, as …

Stroke is the third largest cause of death in the USA (first in Japan), ranking only behind heart
disease and all forms of cancer. It is the leading cause of disability in the United States (ie, …

… shown some early promise, they may be considered less relevant as direct mediators of the
CRS of COVID-19, hence this article will focus on new frontiers in targeting cytokine release. …