[PDF][PDF] Microglia in pain: detrimental and protective roles in pathogenesis and resolution of pain
… causes remarkable microgliosis in the spinal cord. Gliosis is a … also contributes to bone
cancer pain in female rats inoculated … Persistent upregulation of astrocytic connexin-43 (Cx43) …
cancer pain in female rats inoculated … Persistent upregulation of astrocytic connexin-43 (Cx43) …
[HTML][HTML] Neuropathic pain: biomolecular intervention and imaging via targeting microglia activation
A Ji, J Xu - Biomolecules, 2021 - mdpi.com
… These changes result in the up-regulation of IL-1β, NMDAR and … of NP as it inhibits
vincristine-induced hyperalgesia in rats. Its … by inhibiting the activation of rat spinal cord microglia …
vincristine-induced hyperalgesia in rats. Its … by inhibiting the activation of rat spinal cord microglia …
[HTML][HTML] Mechanisms of chemotherapy-induced peripheral neuropathy
R Zajączkowska, M Kocot-Kępska, W Leppert… - International journal of …, 2019 - mdpi.com
… with an increased risk and severity of vincristine-induced neuropathy [201]. … leads to an
increase in the release of presynaptic glutamate at the level of the dorsal horn of the spinal cord …
increase in the release of presynaptic glutamate at the level of the dorsal horn of the spinal cord …
Neuron–microglia interaction by purinergic signaling in neuropathic pain following neurodegeneration
… in the dorsal horn of the spinal cord. A growing body of evidence … with tactile allodynia,
indicating that P2X4R might contribute to … Extracellular ATP triggers tumor necrosis factor-alpha …
indicating that P2X4R might contribute to … Extracellular ATP triggers tumor necrosis factor-alpha …
HCN2 contributes to oxaliplatin-induced neuropathic pain through activation of the CaMKII/CREB cascade in spinal neurons
X Liu, L Zhang, L Jin, Y Tan, W Li, J Tang - Molecular Pain, 2018 - journals.sagepub.com
… allodynia. To examine the role of HCN2 in oxaliplatin-induced neuropathic pain, we detected
HCN2 mRNA and protein expression in the spinal cord … mechanical allodynia in rats. In our …
HCN2 mRNA and protein expression in the spinal cord … mechanical allodynia in rats. In our …
Neuroprotective Effect of Pterocarpus Marsupium Marketed Capsules against Vincristine Induced Neuropathy in Rats
N Shaju - 2017 - repository-tnmgrmu.ac.in
… spinal cord compression. Nocifensive signs crushing of … The analgesic effects of Fucoidan
contributed to an … of L-TAMS completely blocked up-regulation of TNF-α but partially blocked …
contributed to an … of L-TAMS completely blocked up-regulation of TNF-α but partially blocked …
[HTML][HTML] Netazepide, an Antagonist of Cholecystokinin Type 2 Receptor, Prevents Vincristine-Induced Sensory Neuropathy in Mice
A Bernard, M Mroué, S Bourthoumieu, M Boyce… - Pharmaceuticals, 2024 - mdpi.com
… vincristine-induced mechanical allodynia. Netazepide 5 mg/kg restored normal mechanical
sensitivity similar to Veh-Ctrl mice … in the spinal cord during exposure to vincristine leads to …
sensitivity similar to Veh-Ctrl mice … in the spinal cord during exposure to vincristine leads to …
[HTML][HTML] Blockade of IL-6 signaling prevents paclitaxel-induced neuropathy in C57Bl/6 mice
P Huehnchen, H Muenzfeld, W Boehmerle… - Cell death & …, 2020 - nature.com
… Thoracic and lumbar spinal cords from treated mice were … -6 deficient mice develop mechanical
allodynia following PTX … This analysis supports the observation that PTX treatment leads …
allodynia following PTX … This analysis supports the observation that PTX treatment leads …
Upregulation of CCL2 via ATF3/c-Jun interaction mediated the Bortezomib-induced peripheral neuropathy
C Liu, S Luan, H OuYang, Z Huang, S Wu, C Ma… - Brain, behavior, and …, 2016 - Elsevier
… CCL2 upregulation and mechanical allodynia in the rats treated with … BTZ induced mechanical
allodynia and up-regulation of … might contribute to the BTZ-induced mechanical allodynia. …
allodynia and up-regulation of … might contribute to the BTZ-induced mechanical allodynia. …
Current understanding of the molecular mechanisms of chemotherapy-induced peripheral neuropathy
X Chen, Y Gan, NPB Au, CHE Ma - Frontiers in Molecular …, 2024 - frontiersin.org
… A protected the mice against vincristine-induced loss of … was detected in the cerebrospinal
fluid (CSF) of the rats. It resulted in … mice fail to induce up-regulation of dynorphin in the spinal …
fluid (CSF) of the rats. It resulted in … mice fail to induce up-regulation of dynorphin in the spinal …